Kris learned on Tuesday (6/12) that her latest CHOPE chemo regime hasn’t been effective in stopping the progression of the large cell lymphoma. Her PET scan revealed that the cancer has spread and there are some additional tumors in her chest.

1. New chemo treatment: ICE
Her medical team adjusted her treatment and on Wednesday (6/13) started a chemo protocol using ICE:

  • Ifofamide
  • Carboplatin
  • Etoposide

It’s a far more aggressive chemo treatment. In addition to being harder on her organs, it really knocks out her immune system. She receives chemo for 3 days, waits 24-48 hours and then receives a shot of Neulasta to help bring her ANC (white blood cell) levels back up to a near normal level.

Her doctors are also recommending that we shorten the timeline for her transplant. Because the large cell lymphoma is so aggressive, they are going to schedule the transplant for as soon as we can, once the cancer is under control and diminishes.

She’s scheduled to receive another round of ICE in three weeks. If the cancer responds, the transplant will take place as soon as her body has recovered from the chemo treatment.

2. July 5th: 2nd Round of ICE Chemo
After the 2nd round of chemo, we’ll wait 3-4 weeks to allow Kris’ body to recover and heal before she starts the transplant process.

3. Hospitalization and 2 Weeks of Chemo
This chemo serves two purposes: to continue to knock back the CTCL in her blood and to kill her blood and bone marrow in order to prepare her body to accept the donor stem cells and marrow.

4. Transplant
The surgical team will place the donor tissue in Kris. (Important Note: We have not yet identified a donor for Kris in the National Marrow Donor Registry. If you are able, please join the donor registry and/or spread the word among your friends, family and colleagues, asking them to become a donor. It is crucial that a matching donor is identified for Kris. For more information, see the Bone Marrow Donation page.)

5. In-Hospital Recovery
Kris will spend 4-8 weeks in the hospital in a bubble on immunosuppressive drugs to keep the donor stem cells and marrow from rejecting her organs.

6. The Next 100 Days
Kris will split time between a contained home environment and the hospital.

7. The Next 2-5 Years
Kris will undergo various tests and scans.

8. 5 Years and Beyond
Recovery and remission!


8 Responses to “Treatment Plan”

  1. 1 Bev Skrukrud June 1, 2012 at 3:35 am

    Kris and Ken,
    Bob, Heidi and I have been on the bone marrow registry for a long time. Carl just sent in his cheek swabs last week to be put on the registry. I will notify friends and Family of the importance of registering.
    I will pray you can trust God in all of this and daily know His love and Care for you and your loved ones.

  2. 3 Elisabeth Wallace June 11, 2012 at 1:08 pm

    I watched your story on the news this morning and have registered, I hope many more people register to see if they are a potential match… my prayers are with you – and crossing my fingers and toes for a match!!!


  3. 4 Erica June 11, 2012 at 3:27 pm

    I heard Afentra and Danny Boi discussing your situation on the radio this morning. I’m sad to say that I’ve been on the donor registry for a year now and must be one of the 17 million that aren’t a match for you. I will spread word of your story and encourage everyone I can to become a marrow donor. Here’s to beating this disease!

  4. 5 Twilla Winn June 11, 2012 at 6:02 pm

    I had to give my own blood stem cells
    which was purified and given to me with my own stem cells with Dr Pendergas, also now affiliated with KU Med Center.
    Best to you,
    Twilla Winn

  5. 7 C.A.M. Wagner July 1, 2012 at 5:38 pm

    Kris – My heart is with you and I know this battle. I too have had a rare form of cancer and as a result had a bone marrow transplant. Like yourself I had no match on the international registry. I actually had a half match from my little sister at Johns Hopkins. Another friend of mine is getting a cord blood transplant at UVA right now. I’m happy to connect you with my doctors and UVA as well. Let me know. 7036251134. For now I will be praying for you, just as I continue to pray for me and all the cancer patients I know, that we are “Strong in the Lord and in His Mighty Power”. Peace be with you. C.A.M. Wagner

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